Jan Schejbal wrote: Restarting the browser isn't an attractive option with 50+ tabs open.
But you've already shown you have a workaround - using the no-remote switch.
What'd be wrong with setting up a few development profiles - with and without extensions and/or any combo of such?
Natch, if there's some kind of tab interaction, you will have to tread the deadly path of isolating that.... but we've all had to run that gauntlet, with other extensions etc etc. NS isn't an orphan there

Also just thinking aloud...
Security and convenience don't meld well in Fx. Or in any other security-centred application.
NS/Fx is a security tool primarily.
Restartless tools are generally for convenience in my experience. My favourite little one? The Fx extension Restartless restart 8

~Informaction's spam filter too antsy for me to make a click link for you - even more irony
